By Anthony J. Rothschild
Psychotic melancholy is a perilous and debilitating disease that, tragically, usually has deadly results. reviews point out that among sixteen% and fifty four% of all depressed adults be afflicted by a psychosis. whereas this is totally treatable, hundreds of thousands of instances stay misdiagnosed or ignored as a result of an absence of curiosity and understanding between clinicians, the pharmaceutical undefined, and the nationwide Institute of psychological healthiness. because the first complete consultant to hide evaluate, therapy, and administration of sufferers with psychotic melancholy, scientific guide for analysis and therapy of Psychotic melancholy, via Dr. Anthony Rothschild, is a useful source for either clinicians and scholars. Drawing on his personal event in medical care and cautious attention of the prevailing clinical literature, Dr. Rothschild systematically describes the historical past, epidemiology, and attainable organic factors of psychotic melancholy and descriptions numerous techniques for analysis and overview. He then bargains a pragmatic consultant for individualized remedy innovations for psychotic melancholy, akin to electroconvulsive remedy, psychotherapy, and up to date breakthroughs in pharmacologic therapy. moreover, Dr. Rothschild identifies problems with care and administration for particular sufferer populations together with seniors, youngsters, ladies within the postpartum, and sufferers in danger for suicide in various remedy settings. every one bankruptcy comprises the subsequent gains to stress the information and extra improve studying: unique tables and charts Key medical issues that summarize the most principles of the bankruptcy A advised studying record of books and periodicals that handle related themes research and evaluate of correct medical reports Dr. Rothschild has spent greater than 25 years treating sufferers with psychotic melancholy and learning the demanding situations inherent in diagnosing and handling this severe ailment. His findings are compiled during this easy-to-read, evidence-based guide which may profit clinicians in any respect degrees of teaching, together with psychiatrists, psychologists, neurologists, internists, relatives and normal practitioners, nurses, social employees, and medical scholars. whereas a lot is still mentioned in regards to the nature of psychotic melancholy as a special ailment, the prevailing wisdom approximately this is simply too major to be neglected. the single entire handbook of its style, medical handbook for analysis and remedy of Psychotic melancholy is a crucial reference for any psychiatric surroundings.
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Extra info for Clinical Manual for the Diagnosis and Treatment of Psychotic Depression
20 Clinical Manual for Diagnosis and Treatment of Psychotic Depression Table 2–2. Epidemiology 21 bipolar illness in the frequency of hallucinations and delusions during depression (Beigel and Murphy 1971; Kathol and Winokur 1977; Winokur 1984). 01). However, the authors did not report whether these patients were in the manic or depressed phase of the illness. Beigel and Murphy (1971) did not find a relationship between psychotic depression and polarity, in part because psychosis itself was a criterion for inclusion in the study.
In an inpatient sample of depressed adolescents, 45% of the adolescents had psychotic features (Haley et al. 1988). Prevalence of Psychotic Depression in Patients With Unipolar Versus Bipolar Disorder Table 2–2 summarizes findings of studies that examined the prevalence of psychotic features in patients with unipolar or bipolar depression. 001). These results are interesting in light of other studies that indicate that when a patient with bipolar disorder gets depressed, the depressed episode is likely to be an episode with psychotic features (see Chapter 5, “Diagnosis and Assessment”).
1986; Sapru et al. 1989). This enzyme has been hypothesized to play an impor- 28 Clinical Manual for Diagnosis and Treatment of Psychotic Depression Table 3–2. Gene candidates for psychotic depression Dopamine-β-hydroxylase gene (adenosine allele) Serotonin transporter gene; 5-HT1A, 5-HT2A, 5-HT2C receptor genes Dopamine D4 receptor gene (DRD4 allele 7) Glycogen synthase kinase–3 gene (beta isoform) tant role in why some depressed patients become psychotic (Schatzberg et al. 1985) (see Chapter 4, “Biology”).